Low-Dose Naltrexone (LDN) has emerged as a promising medication for immune system regulation and inflammation reduction. The medical community first created LDN to treat opioid addiction, but researchers are now investigating its therapeutic applications for autoimmune diseases, chronic pain management, and inflammatory conditions. When we talk about low-dose naltrexone, we mean doses that are a 10th or less of the standard dose of Naltrexone. Most research studies have used 4.5mg per day. Doses range from 0.001mg – 16 mg in clinical practice.
LDN blocks opioid receptors temporarily, which causes the body to increase its natural pain-regulating compounds, endorphins and enkephalins. Endorphins are your natural peptides produced in many cells, which regulate cell growth, including your immune cells. Many patients who have autoimmune disease tend to have low levels of endorphins, Met-enkephalin, aka opioid growth factor (OGF), an important factor in inflammation reduction.
Opioid receptors are in the central and the peripheral nervous system, the GI tract, and on lymphocytes. By using LDN, you receive a brief blockade, creating a rebound effect, giving you more endorphins, including OGF, and increased production of the OGF receptors. The mechanism regulates immune system balance to decrease the excessive inflammatory reactions that occur in conditions such as multiple sclerosis, rheumatoid arthritis (RA), Lupus, fibromyalgia, and Crohn’s disease, to name a few.
LDN has shown the ability to boost neurological function while simultaneously enhancing mood through its effects on neurotransmitters. People with chronic diseases who take LDN experience decreased pain levels, increased energy, and enhanced general wellness.
LDN stands out because of its possible use as a cancer treatment. Research is emerging showing that LDN may help control tumor progression while boosting the body’s cancer cell elimination capabilities through improved immune surveillance.
LDN presents a promising solution for people who want to decrease inflammation naturally while supporting their long-term wellness. Before adding LDN to a treatment plan, you should consult a hormone specialist located at Axios Health and Wellness, located at 700 Ken Pratt Blvd Suite 108, Longmont, CO 80501, or call 720-899-9400.